Doctor's Best Stabilized R-Lipoic Acid with BioEnhanced NA-RALA 100mg 60 Capsules

Doctor's Best Stabilized R-Lipoic Acid with BioEnhanced NA-RALA 100mg 60 Capsules
Alpha-lipoic acid (ALA) is a sulfur–containing fatty acid that functions as a co-enzyme in the metabolism of carbohydrates and in this way is similar to B-complex vitamins. ALA functions as both a water and fat soluble antioxidant. It is also a key metabolite in the glucose pathway in the cell (turning glucose into energy). The body does produce LA on its own; however, internal LA production may not always be optimal.
Benefits:
Promote Healthy Carbohydrate Management
‘The universal antioxidant’ - RLA is the ideal antioxidant. It has the ability to quench a wide variety of free radicals and support functioning of other antioxidants. It is soluble in both water and fat and is able to recycle antioxidant nutrients such as Vitamin C and E
Helps support the body’s defence against free radicals
Helps maintain healthy glucose metabolism – key factor in cellular processes that metabolize glucose for energy and helps maintain healthy blood sugar levels
Supports healthy ageing – supports improved mitochondrial function and decreased free radical damage
Supports cognitive function and brain health – ageing is associated with oxidative stress in the brain. Studies have shown longer term memory was enhanced by LA
Supports eye health – exceptionally suitable for supporting the retina of the eye. Recommended for smokers as toxins in cigarette smoke are harmful to the retina of the eye
Supports cardiovascular health – studies show support for helping maintain healthy weight and healthy lipid metabolism
Best Stabilized R-Lipoic Acid contains BioEnhanced® Na-RALA, the sodium salt of R-Lipoic Acid. Unlike pure RLA, BioEnhanced® Na-RALA is a stabilized form of RLA that won’t degrade at high temperatures. It is more bioavailable than regular RLA and has no solvent residues.
LA occurs in two forms, designated as ‘R’ and ‘S’. Studies suggest that RLA, the natural form, is more biologically active than the ‘S’ form. The RLA in this product is stabilized with Na (sodium). However, one serving of this product contains less than 1% of the daily value for sodium, an insignificant contribution to dietary sources. The sodium in this product is unlikely to affect blood pressure levels.
Highlights:
The universal antioxidant  
Supports cognitive function and brain health
Supports cardiovascular health
Directions:
Dose (adults): Take 1 capsule daily preferably on an empty stomach, or as recommended by a nutritionally-informed physician.
Safety:
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Storage:
Store in a cool dry place.
FAQ:
What is BioEnhanced™ Na-RLA Stabilized R-Lipoic Acid?
Alpha-lipoic acid comes in two forms, designated as “R-lipoic acid” and “S-lipoic acid.” R- and S- lipoic acid are enantiomer isomers––molecules that appear as mirror images of each other. R-lipoic acid is naturally synthesized by humans, animals, and plants. S-lipoic acid is formed during chemical synthesis of alpha-lipoic acid, producing a “racemic” mixture of the two enantiomers that is often used in clinical studies on alpha-lipoic acid. Pharmacokinetic studies have shown that R-lipoic acid is more bioavailable than the S- form.1 For example, following single oral doses of 50 to 600 mg of racemic LA, maximum serum levels of the R- form were 40 to 50% higher than the S- lipoic form.
Best Stabilized R-Lipoic Acid contains BioEnhanced™ Na-RLA, the sodium salt of R-Lipoic acid (RLA). Pure RLA is a very unstable molecule that has a tendency to polymerize with exposure to heat, light, and moisture. This presents problems for those wishing to supplement with RLA, since any of these conditions can lead to deactivation of the beneficial activity of alpha-lipoic acid. Unlike pure RLA, BioEnhanced™ Na-RLA is a stabilized form of RLA that won’t degrade at high temperatures. By taking the sodium salt of RLA, its solubility is increased and it has an improved dissolution in the body. It is more bioavailable than regular RLA and has no solvent residues.
Note regarding sodium: The RLA in this product is stabilized with Na (sodium). However, one serving of this product contains less than 1% of the Daily Value for sodium, an insignificant contribution to dietary sources. Research suggests that sodium may impact blood pressure in some individuals only when it is consumed as sodium chloride (NaCl, table salt) and not in other forms. The sodium in this product is unlikely to affect blood pressure levels.
Why include D-Biotin ?
Best Stabilized R-Lipoic Acid includes optically pure D-Biotin, the natural form of biotin. D-Biotin is a water-soluble vitamin and member of the vitamin B-complex that aids in the utilization of other B-complex vitamins. Integral to many of the activities of enzymes in the human body, D-biotin is necessary for the breakdown and conversion of fatty acids and carbohydrates into energy, allowing for the production of fats and excretion of protein breakdown products. Long-term administration of lipoic acid can lower the activities of the biotin-dependent enzymes pyruvate carboxylase and beta-methylcrotonyl-CoA carboxylase by competing with biotin.4 Supplementing with LA may thus increase the body's requirements for this vitamin.